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Metaphone
I. Lvg Command:
shell> lvg -f:m -F:1:2
II. Test Cases:
neurologist|NRLJST
hypokalemic|PKLMK
rutgers|RTJRS
college|KLJ
116|
mutagenic|MTJNK
neighbors|NBRS
environmental|ENFRNM
administered|ATMNST
resumé|RSMÉ
spælsau|SPÆLS
Bathrobes®|B0RBS
5|
Evolène |EFLÈN
©2002|
entrez|ENTRS
medline|MTLN
query|KR
other|O0R
formats|FRMTS
medline|MTLN
format|FRMT
links|LNKS
116|
medline|MTLN
neighbors|NBRS
order|ORTR
this|0S
document|TKMNT
food|FT
chem|XM
toxicol|TKSKL
1993|
oct|OKT
31|
10|
707|
715|
bioassay|BS
of|OF
quinoline|KNLN
fluoroquinoline|FLRKNL
carbazole|KRBSL
methylcarbazole|M0LKRB
and|ANT
ethylcarbazole|E0LKRB
in|IN
newborn|NBRN
mice|MS
weyand|WYNT
eh|E
defauw|TF
mcqueen|MKKN
ca|K
meschter|MSKTR
cl|KL
meegalla|MKL
sk|SK
lavoie|LF
ej|EJ
rutgers|RTJRS
state|STT
university|UNFRST
of|OF
new|N
jersey|JRS
college|KLJ
pharmacy|FRMS
department|TPRTMN
pharmaceutical|FRMSTK
chemistry|XMSTR
piscataway|PSKTW
08855|
0789|
quinoline|KNLN
and|ANT
carbazole|KRBSL
are|AR
among|AMNK
the|0
more|MR
prevalent|PRFLNT
aza|AS
arenes|ARNS
present|PRSNT
as|AS
components|KMPNNT
of|OF
environmental|ENFRNM
pollutants|PLTNTS
both|B0
these|0S
aza|AS
arenes|ARNS
are|AR
hepatocarcinogenic|HPTKRS
to|T
mice|MS
when|WN
administered|ATMNST
in|IN
the|0
diet|TT
hepatocarcinogenic|HPTKRS
potential|PTNXL
of|OF
quinoline|KNLN
is|IS
consistent|KNSSTN
with|W0
its|ITS
mutagenic|MTJNK
activity|AKTFT
in|IN
salmonella|SLMNL
typhimurium|TFMRM
ta100|T
and|ANT
potential|PTNXL
to|T
induce|INTS
unscheduled|UNSKTL
dna|TN
synthesis|SN0SS
uds|UTS
in|IN
rat|RT
hepatocytes|HPTSTS
structure|STRKTR
activity|AKTFT
studies|STTS
with|W0
fluorinated|FLRNTT
quinolines|KNLNS
indicate|INTKT
that|0T
the|0
presence|PRSNS
of|OF
fluorine|FLRN
atom|ATM
at|AT
position|PSXN
of|OF
quinoline|KNLN
may|M
inhibit|INHBT
detoxification|TTKSFK
and|ANT
result|RSLT
in|IN
enhanced|ENHNST
genotoxic|JNTKSK
potency|PTNS
quinoline|KNLN
and|ANT
fluoroquinoline|FLRKNL
were|WR
assayed|ASYT
in|IN
newborn|NBRN
cd|KT
mice|MS
at|AT
total|TTL
dose|TS
of|OF
75|
mumol|MML
to|T
establish|ESTBLX
their|0R
relative|RLTF
tumorigenic|TMRJNK
activity|AKTFT
liver|LFR
tumours|TMRS
developed|TFLPT
in|IN
60|
and|ANT
90|
of|OF
the|0
male|ML
newborn|NBRN
mice|MS
treated|TRTT
with|W0
quinoline|KNLN
and|ANT
fluoroquinoline|FLRKNL
respectively|RSPKTF
the|0
majority|MJRT
of|OF
liver|LFR
tumours|TMRS
observed|OBSRFT
among|AMNK
the|0
quinoline|KNLN
treated|TRTT
mice|MS
were|WR
classified|KLSFT
as|AS
adenomas|ATNMS
in|IN
contrast|KNTRST
liver|LFR
carcinomas|KRSNMS
developed|TFLPT
most|MST
of|OF
the|0
male|ML
mice|MS
treated|TRTT
with|W0
fluoroquinoline|FLRKNL
unlike|UNLK
well|WL
established|ESTBLX
genotoxic|JNTKSK
potential|PTNXL
of|OF
quinoline|KNLN
there|0R
is|IS
limited|LMTT
evidence|EFTNS
for|FR
carbazole|KRBSL
having|HFNK
either|E0R
genotoxic|JNTKSK
or|OR
carcinogenic|KRSNJN
activity|AKTFT
whereas|WRS
carbazole|KRBSL
is|IS
not|NT
mutagenic|MTJNK
towards|TWRTS
several|SFRL
strains|STRNS
of|OF
typhimurium|TFMRM
both|B0
methylcarbazole|M0LKRB
and|ANT
ethylcarbazole|E0LKRB
are|AR
active|AKTF
as|AS
mutagens|MTJNS
in|IN
typhimurium|TFMRM
ta100|T
carbazole|KRBSL
methylcarbazole|M0LKRB
and|ANT
ethylcarbazole|E0LKRB
were|WR
assayed|ASYT
in|IN
primary|PRMR
rat|RT
hepatocytes|HPTSTS
to|T
assess|ASS
their|0R
relative|RLTF
potential|PTNXL
induce|INTS
uds|UTS
in|IN
hepatocytes|HPTSTS
only|ONL
ethylcarbazole|E0LKRB
did|TT
so|S
these|0S
carbazole|KRBSL
derivatives|TRFTFS
were|WR
also|ALS
assayed|ASYT
in|IN
newborn|NBRN
cd|KT
mice|MS
at|AT
total|TTL
dose|TS
of|OF
75|
mumol|MML
neither|N0R
carbazole|KRBSL
nor|NR
either|E0R
of|OF
these|0S
alkylcarbazoles|ALKLKR
produced|PRTST
significant|SNFKNT
tumorigenic|TMRJNK
response|RSPNS
in|IN
this|0S
bioassay|BS
system|SSTM
mesh|MX
terms|TRMS
animal|ANML
animals|ANMLS
newborn|NBRN
biological|BLJKL
assay|AS
carbazoles|KRBSLS
toxicity|TKSST
carbazoles|KRBSLS
analysis|ANLSS
carcinogens|KRSNJN
toxicity|TKSST
carcinogens|KRSNJN
analysis|ANLSS
female|FML
liver|LFR
chemistry|XMSTR
liver|LFR
neoplasms|NPLSMS
pathology|P0LJ
liver|LFR
neoplasms|NPLSMS
chemically|XMKL
induced|INTST
male|ML
mice|MS
mice|MS
inbred|INBRT
strains|STRNS
mutagens|MTJNS
toxicity|TKSST
mutagens|MTJNS
analysis|ANLSS
quinolines|KNLNS
toxicity|TKSST
quinolines|KNLNS
analysis|ANLSS
structure|STRKTR
activity|AKTFT
relationship|RLXNXP
support|SPRT
gov|KF
substances|SBSTNS
quinoline|KNLN
carbazole|KRBSL
fluoroquinoline|FLRKNL
methylcarbazole|M0LKRB
quinolines|KNLNS
mutagens|MTJNS
carcinogens|KRSNJN
carbazoles|KRBSLS
grant|KRNT
support|SPRT
es|ES
02338|
niehs|NS
pmid|PMT
8225128|
ui|U
94041058|
the|0
above|ABF
report|RPRT
in|IN
format|FRMT
documents|TKMNTS
on|ON
this|0S
page|PJ
through|0R
loansome|LNSM
doc|TK