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Imaging Tools for Cancer Research

The goal of our work in Biomedical Imaging is two-fold: One, to develop advanced imaging tools for biomedical research in partnership with the National Cancer Institute and other organizations. Secondly, to conduct research in Content Based Image Retrieval (CBIR) to index and retrieve medical images by image features (e.g., shape, color and texture), augmented by textual features as well. This work includes the development of the CervigramFinder for retrieval of uterine cervix images by image features, SPIRS for retrieval of digitized x-ray images of the spine from NHANES II and a distributed global system (SPIRS-IRMA) for image retrieval by both high-level and detailed features of medical images, in collaboration with Aachen University, Germany.

CBIR is also an aspect of the Image Text Indexing (ITI) project that seeks to automatically index illustrations in medical articles by processing text in figure captions and mentions in the article, as well as image features in the illustrations.

Publications/Tools: 
Antani S, Long LR, Thoma GR, Stanley RJ. Vertebra Shape Classification using MLP for Content-Based Image Retrieval International Neural Networks Society and IEEE Neural Networks Society. 2003 July 2003;:160-65.
Long LR, Thoma GR. Use of Shape Models to Search Digitized Spine X-Rays IEEE Computer-Based Medical Systems. 2000 June;: 255-60.
Long LR, Antani SK, Thoma GR. A Prototype Content-Based Image Retrieval System for Spine X-Rays Proc. 16th IEEE Symposium on Computer-Based Medical Systems. 2003 June;: 156-62.
Long LR, Thoma GR. Indexing of Image Content in Spine X-Rays Proc. of SPIE Storage and Retrieval for Image and Video Databases VIII. 2000 Jan;3972:55-63.
Xu X, Lee DJ, Antani S, Long LR. Localizing Contour Points for Indexing an X-Ray Image Retrieval System Los Alamitos, CA: IEEE Computer Society. 2003 June;: 169-74.
Long RL, Thoma GR. Segmentation and Image Navigation in Digitized Spine X-Rays Proc. SPIE Medical Imaging: Image Processing. 2000 Feb; 3979: 168-79.
Lee DJ, Antani S, Long LR. Similarity Measurement Using Polygon Curve Representation and Fourier Descriptors for Shape-Based Vertebral Image Retrieval Proc. of SPIE Medical Imaging: Image Processing. 2003;5032(3): 1283-91.
Thoma GR. Anatomic Images for the Public May 2003 Technical Report to the LHNCBC Board of Scientific Counselors.
Long LR, Thoma GR. Landmarking and Feature Localization in Spine X-Rays Journal of Electronic Imaging. 2002 Oct; 10(4):939-56.

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