You are here

Knowledge Integration for Bio-Threat Response

Printer-friendly versionPrinter-friendly version
Backer A, Bodenreider O, Karp P, Kelly H, Loranger S, Musen M, Sriram R, Wroe C
Los Alamos White Paper
Abstract: 

Bio-threats require rapid analysis and response to prevent widespread consequences tothe population. The inability to easily link and exploit biological knowledge for both human and automated analysis is a major limitation on the speed of complex knowledge development and bio-threat response. Today, linkage among the vast array of biologicalknowledge repositories is primarily by hand. Key requirements for smooth linkage ofknowledge sources include shared ontologies of concepts and semantic relations,capabilities for unifying terminology and extracting meaningful relations from text, andinference mechanisms to link and unify heterogeneous databases. While research in allthese areas continues, the gaps to the needed knowledge integration technologies areimmense, and would benefit from co-ordinated cross-agency funding.

Backer A, Bodenreider O, Karp P, Kelly H, Loranger S, Musen M, Sriram R, Wroe C. Knowledge Integration for Bio-Threat Response Los Alamos White Paper