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Guest Researcher
Phone Number: (
Expertise and Research Interests: 

Dr. Yoo has been a research computer scientist in OHPCC since September 1998.

His research interests include 3D medical image processing and data visualization, multiscale image analysis, computer vision, computer graphics, computational geometry, and parallel and distributed algorithms for image acquisition, processing, and information display. He also works in statistical and structural pattern analysis through the calculus of scale-space. Dr. Yoo is a program project officer for the Visible Human Project Visible Human Project.

Dr. Yoo has a 1985 AB in Biology from Harvard University, a 1990 MS in Computer Science from the University of North Carolina at Chapel Hill, and a 1996 PhD in Computer Science from the University of North Carolina at Chapel Hill. The title of his Ph.D. thesis is "Image Geometry Through Multiscale Statistics".

Professional Activities: 
  • October 1995 to August 1998: Assistant Professor of Radiology and Research Assistant Professor of Engineering, Department of Radiology, University of Mississippi Medical Center, School of Engineering, University of Mississippi. In this position he was research director of digital simulation and visualization projects for Interventional Magnetic Resonance Imaging in which he coordinated projects in both the Engineering School (CS) and the Medical School (Radiology) with the GE Signa SP surgical MR magnet.  He was also director of radiology information systems, where he integrated the Picture Archiving and Communication Systems (PACS), supervised the implementation of the Radiology Information System (RIS), evaluated digital dictation systems (including voice recognition), and designed and implemented radiology systems and a LAN-WAN network toward campus-wide filmless radiology.
Professional Organizations: 
  • October 1999 to the present -- Member: ACR DICOM Standards Working Group 18 on Clinical Trials and Education, American College of Radiologists, Philadelphia, PA
  • February 2004 to the present -- Founding Member: Insight Software Consortium, Clifton Park, NY
  • June 2011 to the present -- Program Committee Member, Mathematical Methods in Biomedical Image Analysis Computing 2011, Breckenridge, CO
  • January 2011 to the present -- International Program Committee Member, International Symposium on Visual Computing 2011, Las Vegas, NV
  • September 1999 to 2011 -- Board Member: Washington Area Computer Assisted Surgical Society (WashCAS), Washington, DC
  • October 2010 -- International Program Committee, IEEE Visualization 2010, Salt Lake City, UT
  • December 2009 -- Program Committee Member, IEEE Workshop on Applications of Computer Vision 2009, Snowbird, UT
  • December 2008 and 2009 -- International Program Committee Member, International Symposium on Visual Computing 2008, 2009, Las Vegas, NV
  • September 2009 -- Workshop Chair: Microscopic Image Analysis with Applications In Biology, MIAAB 2009, Lister Hill National Center for Biomedical Communications,  NLM, NIH,  Bethesda, MD
  • October 2008 -- Conference Committee Member, Co-Chair: Posters, IEEE Visualization 2008, Columbus, OH
  • October 2008 -- Workshop Chair: Understanding Federal Funding – Agencies, Initiatives, and Peer Review, IEEE Visualization 2008, Columbus, OH
  • October 2008 -- International Program Committee Member, Eurographics Workshop on Visual Computing and Biomedicine 2008, Delft, Netherlands
  • September 2008 -- Workshop Chair: Understanding NIH – Grantsmanship, Programs, and Peer Review, MICCAI 2008, New York, NY
  • November 2007 -- International Program Committee Member, IEEE/NIH BISTI 2007 - Life Science Systems & Applications 2007, Bethesda, MD
  • October 2007 -- International Program Committee Member, IEEE Visualization 2007, Sacramento, CA
  • September 2004 to October 2006 -- Executive Committee Member: NIH-NSF Visualization Research Challenges, Washington, DC
  • October 2006 -- International Program Committee, Conference Committee Member, Co-Chair: Workshops, IEEE Visualization 2006, Baltimore, MD
  • August 2006 -- International Program Committee Member, Volume Graphics 2006, Boston, MA
  • March 2006 -- Panelist – Open Source to Open Science, Open Source Strategy for Multi-Center Image Management 2006, Las Vegas, NV
  • February 2006 -- Panelist – Open Source Software, SPIE Medical Imaging 2006, San Diego, CA
  • Ocober 2005 -- Technical Committee Member, Conference Committee Member, Co-Chair, Workshops Venue, IEEE Visualization 2005, Minneapolis, MN
  • July 2005 -- Tutorial Chair:  Modern Techniques for Implicit Modeling, ACM SIGGRAPH 2005, Los Angeles, CA
  • February 2005 -- Panelist – Open Source + Open Data = Open Science, SPIE Medical Imaging 2005, San Diego, CA
  • October 2004 -- Conference Committee Member, Co-Chair, Tutorials Venue, IEEE Visualization 2004, Austin, TX
  • March 2004 -- Keynote Panelist – From Open Source to Open Science, Society for Computer Applications in Radiology 2004, Vancouver, BC, Canada
  • October 2003 -- Conference Committee Member, Co-Chair, Tutorials Venue, IEEE Visualization 2003, Seattle, WA
  • July 2003 -- Invited Special Sessions Chair:  Truth Before Beauty:  Guiding Principles for Medical and Scientific Visualization, ACM SIGGRAPH 2003, San Diego, CA
  • July 2003 -- Tutorial Chair:  Beyond Blobs:  Recent Advances in Implicit Surfaces, ACM SIGGRAPH 2003, San Diego, CA
  • June 2003 -- Technical Committee Member, Scale Space Symposium 2003, Isle of Skye, the United Kingdom
  • January 2003 -- Tutorial Lecturer:  ITK, SPIE Medical Imaging 2003, San Diego, CA
  • October 2002 -- Tutorial Lecturer:  ITK, IEEE Visualization 2002, Boston, MA
  • August 2002 -- Tutorial Chair:  Beyond Blobs:  Recent Advances in Implicit Surfaces, ACM SIGGRAPH 2002, San Antonio, TX
  • August 2002 -- Tutorial Chair: From Transfer Functions to Level Sets:  Advanced Topics in Volume Image Processing, ACM SIGGRAPH 2002, San Antonio, TX
  • October 2001 -- Tutorial Chair:  From Transfer Functions to Level Sets:  Advanced Topics in Volume Image Processing, IEEE Visualization 2001, San Diego, CA
  • October 2001 -- Technical Committee Member, VISIM Workshop on Information Retrieval and Explorations from Large Medical Image Collections, Utrecht, the Netherlands
  • August 2001 -- Tutorial Chair:  Image Processing for Volume Graphics, ACM SIGGRAPH 2001, Los Angeles, CA
  • July 2001 -- Technical Committee Member and Session Chair, The 14rd IEEE Computer Based Medical Systems Symposium, Bethesda, MD
  • February 2001 -- Technical Committee Member, SIAM Symposium on Parallel Processing, Norfolk, VA
  • October 2000 -- Tutorial Chair:  Image Processing for Volume Graphics and Analysis, IEEE Visualization 2000, Salt Lake City, UT
  • October 2000 -- Panelist – Medical Imaging in Cancer Treatment, American College of Radiologists Information Network, Fall 2000 Meeting, Alexandria, VA
  • October 2000 -- Technical Committee Member and Session Chair, The 3rd Visible Human Conference, NLM/NIH, Bethesda, MD
  • October 1999 -- Technical Committee Member and Session Chair, Applied Imagery and Pattern Recognition, the 28th AIPR Workshop, Washington, DC
  • January 1999 – October 2002 -- Medical Information Training Program Faculty/Fellow Search Committee, Lister Hill National Center for Biomedical Communications, NLM/NIH, Bethesda, MD
  • July 1998 -- Tutorial Chair:  3D Visualization in Medicine, ACM SIGGRAPH 98, Orlando, FL
  • July 1993, 1994 -- Tutorial Chair and Lecturer:  Three-Dimensional Visualization of Medical Data, ACM SIGGRAPH 93, Anaheim, CA, SIGGRAPH 94, Orlando, FL
  • September 1992 - May 1994 -- Member: Faculty Search Committee, Department of Computer Science, University of North Carolina at Chapel Hill

Journal Referee:

  • Guest Editor: Journal of Medical Image Analysis
  • IEEE International Conference on Visualization
  • Medical Image Computing and Computer Assisted Intervention
  • IEEE Computer Graphics and Applications
  • IEEE Transactions on Visualization and Computer Graphics
  • IEEE Transactions on Biomedical Engineering
  • Eurographics Computer Graphics Forum
  • Elsevier Computer Methods and Programs in Biomedicine
  • Elsevier Computers in Biology and Medicine
  • Computer Vision and Image Understanding
  • IEEE Transactions on Medical Imaging
  • Graphics Interface
  • Journal for Graphics, Modeling, and Image Processing
  • Journal for the American Informatics Association (JAMIA)
Honors and Awards: 

Terry Yoo was awarded the Hubert H. Humphrey Award for Service to America by U.S. Department of Health and Human Services Secretary Kathleen Sebelius at the June 5, 2014, HHS Departmental Awards Ceremony. Sebelius cited his "leadership in open science through ITK [the Insight Toolkit] as the public software standard for 3-dimensional biomedical image analysis and for all the patients who have benefited." This is one of the highest awards given annually to select individuals within HHS who contribute to the common good and well-being of our nation's citizens through leadership and service.

When NLM sponsored its Visible Human Project (VHP) in the 1990s, it was the most comprehensive study of human anatomy ever attempted. The analysis of its inordinately large data sets far exceeded the software and computing capabilities of the time. In response, Yoo proposed the creation of a public software resource for performing registration (image alignment) and segmentation (image partitioning) of biomedical images. He assembled a consortium of companies and universities that developed ITK. During the past 15 years, ITK has expanded to apply to a wide variety of applications including surgical planning, cancer detection and diagnosis, remote sensing of satellite imagery, segmentation and analysis of cosmological data, 3D microscopy and microanalysis, and even handwriting recognition. The ITK software library comprises nearly 1.5 million lines of C++ code with over 5,000 downloads every month from more than 25 countries.

In addition to his ITK work, Yoo explores advanced topics in image science such as nanometer 3D analysis of microscopy data on the infectious nature of HIV, the use of custom 3D printing in patient-specific surgical instrumentation, and computer vision methods for medication identification to promote consumer safety.

Publications/Tools by Terry Yoo: 
Caban JJ, Liao D, Yao J, Mollura DJ, Gochuico B, Yoo TS. Enhancing image classification models with multimodal biomarkers. In: Summers RM, van Ginneken B, editors. Proceedings of SPIE Medical Imaging 2011: Computer-Aided Diagnosis; 2011 Feb 12-17; Lake Buena Vista (Orlando area), Florida;7963:9 pages. DOI: 10.1117/12.878084.
Mann D, Caban JJ, Stolka PJ, Boctor EM, Yoo TS. Multidimensional transfer functions for effective visualization of streaming ultrasound and elasticity images. In: Wong KH, Holmes DR III, editors. Proceedings of SPIE Medical Imaging 2011: Visualization, Image-Guided Procedures, and Modeling; 2011 Feb 12-17; Lake Buena Vista, Florida;7964:1-8. DOI:10.1117/12.878935.
Liu J, Subramanian KR, Yoo TS. Temporal Volume Flow: An Approach to Tracking Failure Recovery. In: Summers RM, van Ginneken B, editors. Proceedings of SPIE Medical Imaging 2011: Computer-Aided Diagnosis; 2011 Feb 12-17; Lake Buena Vista, Florida;7963. SPIE; 2011 Mar 4. DOI: 10.1117/12.878220.
Caban JJ, Rheingans P, Yoo TS. An MRF-based Statistical Deformation Model for Morphological Image Analysis. IEEE Computer Society Workshop on Mathematical Models in Biomedical Image Analysis (MMBIA); 2010 Jun 14; San Francisco:31-8.
Liu J, Subramanian K, Yoo TS. Accurate motion parameter estimation for colonoscopy tracking using a regression method. In: Karssemeijer N, Summer RM, editors. Proceedings of SPIE Medical Imaging 2010: Computer-Aided Diagnosis; 2010 Feb 13-18; San Diego;7624:11 pages. DOI: 10.1117/12.844433.
Liu J, Subramanian K, Yoo TS. Region flow: a multi-stage method for colonoscopy tracking. Med Image Comput Comput Assist Interv. 2010;13(Pt 2):505-13.
Yoo TS, Silver D, Correa C, Chen D, Moran A. Volumetric Bodies - the Exhibition. IEEE VisWeek 2009 Interactive Demo & Art Exhibit; 2009 Oct 12-16; Atlantic City, New Jersey.
Bennett AE, Narayan K, Shi D, Hartnell LM, Gousset K, He H, Lowekamp BC, Yoo TS, Bliss D, Freed EO, Subramaniam S. Ion-abrasion scanning electron microscopy reveals surface-connected tubular conduits in HIV-infected macrophages. PLoS Pathog. 2009 Sep;5(9):e1000591. doi: 10.1371/journal.ppat.1000591. Epub 2009 Sep 25.
Du H, Yoo TS, Qin H. PDE-based medial axis extraction and shape manipulation of arbitrary meshes. Journal of Systems Science and Complexity. 2008 Dec;21(4):601-17.
Liu J, Subramanian K, Yoo T, Van Uitert R. A Stable Optic-flow Based Method for Tracking Colonoscopy Images. Proceedings of MMBIA 2008, the IEEE Computer Society Workshop on Mathematical Methods in Biomedical Image Analysis; 2008 Jun 23-28; Anchorage, Alaska. DOI: 10.1109/CVPRW.2008.4562990.