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Imaging Tools for Cancer Research

The goal of our work in Biomedical Imaging is two-fold: One, to develop advanced imaging tools for biomedical research in partnership with the National Cancer Institute and other organizations. Secondly, to conduct research in Content Based Image Retrieval (CBIR) to index and retrieve medical images by image features (e.g., shape, color and texture), augmented by textual features as well. This work includes the development of the CervigramFinder for retrieval of uterine cervix images by image features, SPIRS for retrieval of digitized x-ray images of the spine from NHANES II and a distributed global system (SPIRS-IRMA) for image retrieval by both high-level and detailed features of medical images, in collaboration with Aachen University, Germany.

CBIR is also an aspect of the Image Text Indexing (ITI) project that seeks to automatically index illustrations in medical articles by processing text in figure captions and mentions in the article, as well as image features in the illustrations.

Xue Z, You D, Chachra S, Antani SK, Long LR, Demner-Fushman D, Thoma GR. Extraction of endoscopic images for biomedical figure classification. Proc. SPIE. 9418, Medical Imaging 2015: PACS and Imaging Informatics: Next Generation and Innovations, 94180P. (March 17, 2015) doi: 10.1117/12.2081033.
Song D, Kim E, Huang X, Patruno J, Munoz-Avila H, Heflin J, Long LR, Antani SK. Multimodal entity coreference for cervical dysplasia diagnosis. IEEE Transactions on Medical Imaging, 34(1), January 2015, 229-245.
Demner-Fushman D, Antani S, Kalpathy-Cramer J, Müller H. A decade of community-wide efforts in advancing medical image understanding and retrieval. Comput Med Imaging Graph. 2015 Jan;39:1-2. doi: 10.1016/j.compmedimag.2014.12.002.
Xue Z, Bryant B, Long LR, Sari-Sarraf H, Thoma GR, Wachtel M. A Client-Server Tool for Automatic Fast GPU-based Detection of Squamous Epithelium Tissue Regions in Histology Images [Poster]. RSNA 2014. Chicago, USA, Nov 30-Dec 5, 2014
Rondonotti E, Koulaouzidis A, Karargyris A, Giannakou A, Fini L, Soncini M, Pennazio M, Douglas S, Shams A, Lachlan N, Zahid A, Mandelli G, Girelli C. Utility of 3-dimensional image reconstruction in the diagnosis of small-bowel masses in capsule endoscopy (with video). Gastrointest Endosc. 2014 Oct;80(4):642-51. doi: 10.1016/j.gie.2014.04.057. Epub 2014 Jul 3.
KC S, Wendling L, Antani SK, Thoma GR. Scalable arrow detection in biomedical images. Pattern Recognition (ICPR), 2014 22nd International Conference; pp 3257-62. DOI: 10.1109/ICPR.2014.561
You D, Antani SK, Demner-Fushman D, Thoma GR. A MRF Model for Biomedical Image Segmentation. CBMS 2014. May 2014.
You D, Antani SK, Demner-Fushman D, Thoma GR. A Contour-based Shape Descriptor For Biomedical Image Classification and Retrieval. Proceedings of SPIE 2014, Vol. 9021, Document Recognition and Retrieval XXI. February 2014;9021.
Karargyris A, Rondonotti E, Mandelli G, Koulaouzidis A. Evaluation of 4 three-dimensional representation algorithms in capsule endoscopy images. World J Gastroenterol. 2013 Nov 28;19(44):8028-33. doi: 10.3748/wjg.v19.i44.8028.
You D, Antani SK, Demner-Fushman D, Thoma GR. Does figure-text improve biomedical image retrieval [Poster]. NIH Intramural Research Festival, Bethesda MD, November 6-8, 2013.