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Figure content analysis for improved biomedical article retrieval.

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You D, Apostolova E, Antani SK, Demner-Fushman D, Thoma GR
Proceedings of SPIE Electronic Imaging Science and Technology, Document Retrieval and Recognition XVI. January 2009;7247:7247 0V(1-10).
Abstract: 

Biomedical images are invaluable in medical education and establishing clinical diagnosis. Clinical decision support (CDS) can be improved by combining biomedical text with automatically annotated images extracted from relevant biomedical publications. In a previous study we reported 76.6% accuracy using supervised machine learning in automatically classifying images, by combining figure captions and image content to find clinical evidence. Image content extraction is traditionally applied on entire images or on pre-determined image regions. Figure images in articles vary greatly in modality and content, which limits the benefit of whole image extraction beyond gross categorization for CDS. However, image text and overlaid annotations identify the regions of interest (ROI) on the image that are referenced in the caption or discussion in the article text. We have previously reported 72.02% accuracy in text and symbols localization but in that experiment we did not exploit the referenced image locality. In this work we combine article text analysis and figure image analysis for localizing pointers (arrows, symbols) to extract ROI pointed that can then be used to obtain meaningful image content and associate it with the identified biomedical concepts for improved (text and image) content-based retrieval of biomedical articles. Biomedical concepts are identified using National Library of Medicine's Unified Medical Language System (UMLS) Metathesaurus. Our methods report an average precision and recall of 92.3% and 75.3%, respectively on identifying pointing symbols in images from a randomly selected image subset made available through the ImageCLEF 2008 campaign.

You D, Apostolova E, Antani SK, Demner-Fushman D, Thoma GR. Figure content analysis for improved biomedical article retrieval. Proceedings of SPIE Electronic Imaging Science and Technology, Document Retrieval and Recognition XVI. January 2009;7247:7247 0V(1-10).